Welcome to the Cram Lab
Interactions between cells and their extracellular environment play an essential role in controlling tissue architecture, cell survival, and cell migration. These processes are important for normal animal development and are disrupted during cancer progression.
Integrins are cell surface proteins that sense the extracellular microenvironment and signal to the cell to control differentiation, survival and migration of cells. In animals there are multiple integrins with specialized and overlapping roles in various cell types.
Erin J. Cram, Ph.D.
Principal Investigator
